Pfizer reports ongoing manufacturing shortage of Premarin vaginal cream
Pfizer Canada reports its Premarin (conjugated estrogens) 0.625 mg vaginal cream is in an actual shortage after a disruption in manufacturing. The actual shortage began Jun 30, 2026 and no estimated end date is given.
Premarin cream is widely used for menopause-related vaginal symptoms — patients and pharmacies should check stock and alternatives while the shortage runs.
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Official source: Pfizer reports ongoing manufacturing shortage of Premarin vaginal cream (opens in a new tab) — Health Product Shortages Canada