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A novel mRNA cancer vaccine helps cut the chances of melanoma tumor recurrence in major study

Moderna and Merck's personalized mRNA vaccine intismeran cut the risk of melanoma returning by 42 per cent two years after surgery, in a study of more than 1,100 people with high-risk melanoma. Two years on, 82 per cent of vaccinated patients were recurrence-free, versus 70 per cent on Keytruda alone. The companies are discussing approval with regulators; full results were due at a European oncology meeting in Madrid.

A personalized mRNA vaccine, matched to each patient's tumour, is moving toward approval after a large trial showed a clear gain in living without recurrence.

Full results presented at ESMO meeting, Madrid: Oct 24, 2026 All deadlines

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Azurion 7 Systems

Philips has issued a notice regarding Azurion 7 systems that may contain unauthorized solid-state drives. These incorrect components could lead to system failures, including the loss of imaging capabilities, motorized movement issues, or the inability to access and store patient data.

If you use an Azurion 7 system, be aware that unauthorized drives may cause sudden equipment failure or loss of patient data.

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i-STAT hs-TnI Cartridge

Abbott has issued a recall for specific lots of i-STAT hs-TnI cartridges due to manufacturing variability. These cartridges may produce falsely elevated cardiac troponin I results because of reduced interference mitigation. There is no evidence of falsely low test results.

Check your i-STAT hs-TnI cartridge lots against the recall list and stop using any affected units immediately.